5-Amino-1MQ.

Price range: £41.00 through £76.00

A small-molecule selective inhibitor of nicotinamide N-methyltransferase (NNMT). Studied alongside peptide GLP-1 agonists in metabolic-research models.

What’s in your box
Lyophilised vial | BAC water | 10 insulin syringes | 4 alcohol wipes | Reconstitution card | Plain Royal Mail box
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Quick answers to the most-asked questions

Everything researchers usually message us about, answered on the page.

  • 🛡 Do you test your products? Every batch is verified through Janoshik HPLC testing.

Yes – every batch. Every product we supply is independently HPLC-verified by Janoshik Analytical, a Czech specialist peptide-analysis laboratory unaffiliated with us. Reported purity is consistently above 99%.

Where a Janoshik report has been issued for the current batch, the printed Certificate of Analysis is supplied with the order. Otherwise the verification record is published on our Purity page.

Every COA carries a unique verification key you can authenticate against Janoshik’s own portal at janoshik.com – so you don’t have to take our word for it. We’re the only UK supplier writing publicly about how to read these reports: how to read a Janoshik HPLC report ›

  • 💧How to mix BAC + powderReconstitution in 4 steps
  1. Wipe the vial top. Use one of the alcohol prep wipes from the box. Let it dry.
  2. Draw 2 mL BAC water. Use one of the insulin syringes. Insert the needle through the rubber stopper of the BAC water vial.
  3. Inject the BAC slowly down the inside wall of the peptide vial. Don’t squirt directly onto the powder.
  4. Swirl gently. Don’t shake. Wait 30 seconds for full dissolution. Refrigerate.

Use the reconstitution card on the inside of the box lid as your reference next time.

  • 💉How to use the penDose dial, clicks, priming
  1. Attach a fresh needle. Wipe the needle end of the pen with an alcohol prep wipe. Screw a foil-wrapped needle from the box onto the threaded tip.
  2. Prime the needle. Dial up 1 click, point the needle upwards, press the dose button. A drop of solution at the needle tip confirms the pen is primed and any air is expelled.
  3. Dial your research dose. Each click on the dose dial delivers a fixed increment. Click resolution is typically 0.5–1 mg per click depending on calibration; the dose window shows your total dialled dose. For example, a 6 mg research dose is roughly 6–12 clicks.
  4. Administer at the route used in published research. Cohort protocols use subcutaneous administration (abdomen, thigh, upper arm). Hold for ~6 seconds before withdrawing.
  5. Discard the needle in a sharps container. Cap the pen and return to refrigerated storage.

One pen lasts the number of doses shown in the protocol cards above for your selected size. When it’s empty, drop a refill cartridge into the same pen body – price for your size is in the calculator at the top.

Research use only. Procedure drawn from published cohort protocols. We do not provide medical or human-use guidance.

  • StorageLyophilised + reconstituted

Lyophilised vial: stable 24+ months at 2–8 °C, sealed and protected from light. Don’t freeze.

Reconstituted (after BAC water): ~30 days at 2–8 °C. Don’t shake. Keep in original glass vial. Discard if cloudy or discoloured.

BAC water bottle: 30 days once opened, refrigerated.

  • 📍Administration in researchRoute used in published studies

Published research literature on 5-Amino-1MQ uses subcutaneous administration in the abdomen, thigh or upper arm in human pharmacokinetic and Phase 2 / 3 studies. Researchers rotate sites between administrations to reduce local tissue stress.

Research use only. The route information above is drawn from published peer-reviewed literature for context. We do not provide human-use guidance, dosing protocols, or administration instructions.

Reference: Neelakantan et al. 2018

  • 🎯What should my dose be?Straight answer, no fluff

The clean answer: follow the protocol cards above. Published research literature on 5-Amino-1MQ uses titration – start low, step up at fixed weekly intervals. The phase highlighted in green is where most published research cohorts settle for ongoing study.

If you’re new to this compound: start at Phase 1 (the lowest dose shown above) for the full duration of that phase, then step up to the next. The titration is what limits the GI side effects reported in the trial – don’t skip it.

If you’ve used this compound before: you already know which phase you’re at. Tap the phase tabs above to see exactly what your dose costs at your selected vial or pen size, plus how long it will last.

If your protocol is non-standard: WhatsApp us before you order. We help researchers work out custom schedules every day and will tell you which size makes most sense for the cadence you’re running. Real human reply, not a chatbot.

Research use only. The dosing described is drawn from published peer-reviewed cohort literature for context. We do not provide medical or human-use guidance. If you are evaluating this compound for human use, consult a qualified medical practitioner. Reference: Neelakantan et al. 2018

Key Information

Compound 5-Amino-1MQ
Research category Metabolic Research
Available sizes 5mg, 10mg, 50mg
Pricing From £30
Format Lyophilised powder in sealed vial
Purity >99% by HPLC (Janoshik Analytical, batch-verified)
Intended use In-vitro laboratory research only. Not for human consumption.

Chemical & Reference Data

Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.

Compound class Small-molecule NNMT inhibitor (5-amino-1-methylquinolinium)
Molecular formula C10H11N2+
Molecular weight 159.21 g/mol (cation)
CAS Registry Number 1979-92-2
PubChem CID 16219527
Receptor / mechanism Selective NNMT (nicotinamide N-methyltransferase) inhibitor.
Reported half-life Reported short serum half-life in published preclinical literature.
Solubility Lyophilised powder reconstitutes in bacteriostatic water or DMSO for laboratory use.
Storage (lyophilised) Stable at 2–8 °C lyophilised for 18+ months.
Storage (reconstituted) Reconstituted: store at 2–8 °C, use within 14 days.
Clinical / regulatory status Preclinical / investigational.

Research Profile

  • Small-molecule NNMT inhibitor
  • Studied in metabolic pathway research
  • Third-party purity tested
  • Research use only

5-Amino-1-methylquinolinium (5-Amino-1MQ) is a small-molecule research compound characterised in preclinical literature as a selective inhibitor of nicotinamide N-methyltransferase (NNMT). Supplied for in-vitro research use only.

The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.

Laboratory Handling

5-Amino-1MQ is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved – do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.

Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.

State Temperature Shelf life
Lyophilised 2–8 °C or −20 °C Up to 24 months
Reconstituted 2–8 °C 4–6 weeks typical

Purity & Verification

Every batch of 5-Amino-1MQ we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik’s records. Reported purity is consistently above 99%.

Related Compounds

Researchers working with 5-Amino-1MQ often work alongside the following compounds in the preclinical literature:

  • AOD9604 – Metabolic Research
  • AICAR – Metabolic Research

Compare 5-Amino-1MQ with Related Compounds

  • Compare 5-Amino-1MQ vs AOD9604 – side-by-side mechanism, pricing and lab handling.
SIZE

10mg, 50mg

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